Manny Pacquiao is a natural southpaw. From very early in his career Pacquiao has fought in a Southpaw stance. His power was evident from early on, however his skills only became complete in the years before his bout with Oscar De La Hoya. When Manny first fought on HBO, he was trying to knock fighters out with one punch, however he developed his widespread arsenal over time.
Manny does through combinations from abnormal Southpaw positions but he is a genuine southpaw with one of the best combination punches in the history of boxing. His attacking ability is very high up the all time great list. His vulnerabilities lie in his lack of defence and the way he jumps and lunges at opponents.